Candida auris: a Review of the Literature

SUMMARYThe emerging pathogen Candida aurishas been associated with nosocomial outbreaks on five continents. Genetic analysis indicates the simultaneous emergence of separate clades of this organism in different geographical locations. Invasive infection and colonization have been detected predominantly in patients in high-dependency settings and have garnered attention due to variable antifungal resistance profiles and transmission within units instituting a range of infection prevention and control measures. Issues with the identification of C. aurisusing both phenotypic and molecular techniques have raised concerns about detecting the true scale of the problem. This review considers the literature available on C. aurisand highlights the key unknowns, which will provide direction for further work in this field.