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Tenofovir alafenamide plus emtricitabine versus abacavir plus lamivudine for treatment of virologically suppressed HIV-1-infected adults: a randomised, double-blind, active-controlled, non-inferiority phase 3 trial

Authors :
Winston, Alan
Post, Frank A
DeJesus, Edwin
Podzamczer, Daniel
Di Perri, Giovanni
Estrada, Vicente
Raffi, François
Ruane, Peter
Peyrani, Paula
Crofoot, Gordon
Mallon, Patrick W G
Castelli, Francesco
Yan, Mingjin
Cox, Stephanie
Das, Moupali
Cheng, Andrew
Rhee, Martin S
Source :
The Lancet HIV; April 2018, Vol. 5 Issue: 4 pe162-e171, 10p
Publication Year :
2018

Abstract

Abacavir and tenofovir alafenamide offer reduced bone toxicity compared with tenofovir disoproxil fumarate. We aimed to compare safety and efficacy of tenofovir alafenamide plus emtricitabine with that of abacavir plus lamivudine.

Details

Language :
English
ISSN :
24054704 and 23523018
Volume :
5
Issue :
4
Database :
Supplemental Index
Journal :
The Lancet HIV
Publication Type :
Periodical
Accession number :
ejs44867666
Full Text :
https://doi.org/10.1016/S2352-3018(18)30010-9