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Tailored frequency-escalated primary prophylaxis for severe haemophilia A: results of the 16-year Canadian Hemophilia Prophylaxis Study longitudinal cohort
- Source :
- The Lancet Haematology; June 2018, Vol. 5 Issue: 6 pe252-e260, 9p
- Publication Year :
- 2018
-
Abstract
- Severe haemophilia A has high morbidity, and treatment, while effective, is very expensive. We report the 16-year follow-up of the Canadian Hemophilia Prophylaxis Study, which examined the effectiveness of tailored frequency-escalated primary prophylaxis with a focus on health outcomes within the domains of body structures and functions, and activities and participation (according to the WHO International Classification of Functioning, Disability and Health [WHO-ICF] framework) and a view to reducing consumption of costly clotting factor, which accounts for more than 90% of the cost of care of severe haemophilia.
Details
- Language :
- English
- ISSN :
- 23523026
- Volume :
- 5
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- The Lancet Haematology
- Publication Type :
- Periodical
- Accession number :
- ejs45505921
- Full Text :
- https://doi.org/10.1016/S2352-3026(18)30048-6