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Use of pentafluorophenyl esters for one-pot protection/activation of amino and thiol carboxylic acids

Authors :
Gayo, Leah M.
Suto, Mark J.
Source :
Tetrahedron Letters; January 1996, Vol. 37 Issue: 28 p4915-4918, 4p
Publication Year :
1996

Abstract

As part of our efforts in the area of combinatorial chemistry, we have been exploring new methods for the construction of combinatorial libraries in a bidirectional fashion. Herein, we describe a new one-pot procedure for the simultaneous protection/activation of amino and thiol carboxylic acids using pentafluorophenyl trifluoroacetate (TFAPfp) and related pentafluorophenyl reagents (FmocPfp and AcPfp).

Details

Language :
English
ISSN :
00404039
Volume :
37
Issue :
28
Database :
Supplemental Index
Journal :
Tetrahedron Letters
Publication Type :
Periodical
Accession number :
ejs45812726
Full Text :
https://doi.org/10.1016/0040-4039(96)00985-9