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Antibacterial Spectrum of a Tetrazole-Based Reversible Inhibitor of Serine β-Lactamases

Authors :
Pemberton, Orville A.
Zhang, Xiujun
Nichols, Derek A.
DeFrees, Kyle
Jaishankar, Priyadarshini
Bonnet, Richard
Adams, Jessie
Shaw, Lindsey N.
Renslo, Adam R.
Chen, Yu
Source :
Antimicrobial Agents and Chemotherapy; May 2018, Vol. 62 Issue: 8
Publication Year :
2018

Abstract

CTX-M is the most prevalent family of extended-spectrum β-lactamases. We recently developed a tetrazole-derived noncovalent inhibitor of CTX-M-9.

Details

Language :
English
ISSN :
00664804 and 10986596
Volume :
62
Issue :
8
Database :
Supplemental Index
Journal :
Antimicrobial Agents and Chemotherapy
Publication Type :
Periodical
Accession number :
ejs46110417
Full Text :
https://doi.org/10.1128/AAC.02563-17