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Rho and Anillin-dependent Control of mDia2 Localization and Function in Cytokinesis
- Source :
- Molecular Biology of the Cell; September 2010, Vol. 21 Issue: 18 p3193-3204, 12p
- Publication Year :
- 2010
-
Abstract
- Diaphanous-related formin, mDia, is an actin nucleation/polymerization factor functioning downstream of the small GTPase Rho. We found that, in addition to the Rho GTPase-mediated activation, the interaction between mDia2 and anillin is required for the localization and function of mDia2 in cytokinesis.
Details
- Language :
- English
- ISSN :
- 10591524 and 19394586
- Volume :
- 21
- Issue :
- 18
- Database :
- Supplemental Index
- Journal :
- Molecular Biology of the Cell
- Publication Type :
- Periodical
- Accession number :
- ejs46603654
- Full Text :
- https://doi.org/10.1091/mbc.e10-04-0324