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Amino acid sequence of human factor D of the complement system
- Source :
- FEBS Letters; January 1984, Vol. 166 Issue: 2 p347-351, 5p
- Publication Year :
- 1984
-
Abstract
- The amino acid sequence of human factor D is proposed from the analysis of the peptides produced by treatment of the factor D with cyanogen bromide, iodosobenzoic acid, trypsin and V‐8 protease. Comparison of the proposed sequence with the sequences of other serine esterases indicated that factor D, although it is a plasma serine esterase, is more closely related to certain proteases not found in the plasma than to other plasma serine esterases of the complement system. For example, 36% and 32% identity in amino acid sequence was found on comparison of factor D with elastase and group‐specific protease, respectively. Whereas only 27% and 18% identity was observed between factor D and the other complement serine esterases, Clr and factor B, respectively.
Details
- Language :
- English
- ISSN :
- 00145793
- Volume :
- 166
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- FEBS Letters
- Publication Type :
- Periodical
- Accession number :
- ejs46676397
- Full Text :
- https://doi.org/10.1016/0014-5793(84)80110-6