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Light-Driven ATP Transmembrane Transport Controlled by DNA Nanomachines
- Source :
- Journal of the American Chemical Society; November 2018, Vol. 140 Issue: 47 p16048-16052, 5p
- Publication Year :
- 2018
-
Abstract
- In nature, biological machines can perform sophisticated and subtle functions to maintain the metabolism of organisms. Inspired from these gorgeous works of nature, scientists have developed various artificial molecular motors and machines. However, selective transport of biomolecules across membrane has remained a great challenge. Here, we establish an ATP transport system by assembling photocontrolled DNA nanomachines into the artificial nanochannels. With alternant light irradiation, these ATP transport lines can selectively shepherd cargoes across the polymer membrane. These findings point to new opportunities for manipulating and improving the mass transportation and separation with light-controlled biomolecular motors, and can be used for other molecules and ions transmembrane transport powered by light.
Details
- Language :
- English
- ISSN :
- 00027863 and 15205126
- Volume :
- 140
- Issue :
- 47
- Database :
- Supplemental Index
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Periodical
- Accession number :
- ejs46876707
- Full Text :
- https://doi.org/10.1021/jacs.8b10527