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Ginsenoside Rg5 overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter: in vitroand in vivostudy

Authors :
Feng, Sen-Ling
Luo, Hai-Bin
Cai, Liang
Zhang, Jie
Wang, Dan
Chen, Ying-Jiang
Zhan, Huan-Xing
Jiang, Zhi-Hong
Xie, Ying
Source :
Journal of Ginseng Research; March 2020, Vol. 44 Issue: 2 p247-257, 11p
Publication Year :
2020

Abstract

Multidrug resistance (MDR) to chemotherapy drugs remains a major challenge in clinical cancer treatment. Here we investigated whether and how ginsenoside Rg5 overcomes the MDR mediated by ABCB1 transporter in vitroand in vivo.

Details

Language :
English
ISSN :
12268453 and 20934947
Volume :
44
Issue :
2
Database :
Supplemental Index
Journal :
Journal of Ginseng Research
Publication Type :
Periodical
Accession number :
ejs47178124
Full Text :
https://doi.org/10.1016/j.jgr.2018.10.007