Failure of Ascorbic Acid to Influence Albuminuria and Hematuria in Nephritis.∗

In 5 patients with hematuria due to acute or subacute nephritis, the administration of ascorbic acid in massive doses over a period of 6 to 10 days sufficient to saturate the body stores had no significant effect on the amount of hematuria or albuminuria. In one case there was a definite decrease but coincidental spontaneous improvement could not be excluded.