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Factors involved in phenoconversion of CYP3A using 4β-hydroxycholesterol in stable kidney transplant recipients
- Source :
- Pharmacological Reports; April 2019, Vol. 71 Issue: 2 p276-281, 6p
- Publication Year :
- 2019
-
Abstract
- •We evaluated the relations of CYP3A phenoconversion with plasma levels of indoxyl sulfate and cytokines.•Higher plasma indoxyl sulfate levels were associated with CYP3A phenoconversion.•Dose adjustment may be needed in patients with CYP3A5*1and high indoxyl sulfate level.
Details
- Language :
- English
- ISSN :
- 17341140
- Volume :
- 71
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Pharmacological Reports
- Publication Type :
- Periodical
- Accession number :
- ejs47565922
- Full Text :
- https://doi.org/10.1016/j.pharep.2018.12.007