A one-pot synthesis of a self-included bisester-functionalized copillar[5]arene

A bisester-substituted copillar[5]arene was synthesized by a one-pot reaction presenting a symmetrical self-included conformation in solution and an asymmetrical structure with only one self-included side in the cavity of pillar[5]arene in the solid state. This compound was characterized by 1D and 2D NMR and X-ray diffraction.