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CD44 splice isoform switching determines breast cancer stem cell state
- Source :
- Genes & Development; 2019, Vol. 33 Issue: 3-4 p166-179, 14p
- Publication Year :
- 2019
-
Abstract
- Zhang et al. show that manipulating the splicing regulator ESRP1 to shift alternative splicing from splice isoform CD44v to CD44s leads to an induction of cancer stem cell properties.
Details
- Language :
- English
- ISSN :
- 08909369 and 15495477
- Volume :
- 33
- Issue :
- 3-4
- Database :
- Supplemental Index
- Journal :
- Genes & Development
- Publication Type :
- Periodical
- Accession number :
- ejs48299869
- Full Text :
- https://doi.org/10.1101/gad.319889.118