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Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6variants
- Source :
- Pharmacogenetics and Genomics; December 2012, Vol. 22 Issue: 12 p858-867, 10p
- Publication Year :
- 2012
-
Abstract
- Prior candidate gene studies have associated CYP2B6516G→T rs3745274 and 983T→C rs28399499 with increased plasma efavirenz exposure. We sought to identify novel variants associated with efavirenz pharmacokinetics.
Details
- Language :
- English
- ISSN :
- 17446872 and 17446880
- Volume :
- 22
- Issue :
- 12
- Database :
- Supplemental Index
- Journal :
- Pharmacogenetics and Genomics
- Publication Type :
- Periodical
- Accession number :
- ejs48718904
- Full Text :
- https://doi.org/10.1097/FPC.0b013e32835a450b