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Bioinformatic and functional analysis of TGFBR1 polymorphisms
- Source :
- Pharmacogenetics and Genomics; April 2009, Vol. 19 Issue: 4 p249-259, 11p
- Publication Year :
- 2009
-
Abstract
- The transforming growth factor- (TGFB) pathway has substantial impact on cellular functions, cell proliferation, and apoptosis. We used bioinformatics, gene expression, and cell biological assays to evaluate the functionality of frequent inherited germline polymorphisms in the TGFB receptor 1 (TGFBR1).
Details
- Language :
- English
- ISSN :
- 17446872 and 17446880
- Volume :
- 19
- Issue :
- 4
- Database :
- Supplemental Index
- Journal :
- Pharmacogenetics and Genomics
- Publication Type :
- Periodical
- Accession number :
- ejs48719330
- Full Text :
- https://doi.org/10.1097/FPC.0b013e32831cb5a7