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Association of a functional polymorphism in the CYP4A11gene with systolic blood pressure in survivors of myocardial infarction
- Source :
- Journal of Hypertension; October 2006, Vol. 24 Issue: 10 p1965-1970, 6p
- Publication Year :
- 2006
-
Abstract
- Survivors of myocardial infarction (MI) are known to have a high prevalence of arterial hypertension which, at the same time, imposes a major risk to such patients. Genetic variants of the arachidonic acid monooxygenase CYP4A11may result in decreased synthesis of 20-hydroxyeicostatetraenoic acid (20-HETE), experimental hypertension and elevated blood pressure levels in humans. The present study aimed to investigate the impact of the functionally relevant T8590C polymorphism of this gene on blood pressure and the prevalence of hypertension in MI patients.
Details
- Language :
- English
- ISSN :
- 02636352 and 14735598
- Volume :
- 24
- Issue :
- 10
- Database :
- Supplemental Index
- Journal :
- Journal of Hypertension
- Publication Type :
- Periodical
- Accession number :
- ejs48867623
- Full Text :
- https://doi.org/10.1097/01.hjh.0000244944.34546.8e