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Congenital lethal motor neuron disease with a novel defect in ribosome biogenesis

Authors :
Butterfield, Russell J.
Stevenson, Tamara J.
Xing, Lingyan
Newcomb, Tara M.
Nelson, Benjamin
Zeng, Wenqi
Li, Xiang
Lu, Hsiao-Mei
Lu, Hong
Gonzalez, Kelly D. Farwell
Wei, Jia-Perng
Chao, Elizabeth C.
Prior, Thomas W.
Snyder, Pamela J.
Bonkowsky, Joshua L.
Swoboda, Kathryn J.
Source :
Neurology (Ovid); April 2014, Vol. 82 Issue: 15 p1322-1330, 9p
Publication Year :
2014

Abstract

We describe a novel congenital motor neuron disease with early demise due to respiratory insufficiency with clinical overlap with spinal muscular atrophy with respiratory distress (SMARD) type 1 but lacking a mutation in the IGHMBP2gene.

Details

Language :
English
ISSN :
00283878 and 1526632X
Volume :
82
Issue :
15
Database :
Supplemental Index
Journal :
Neurology (Ovid)
Publication Type :
Periodical
Accession number :
ejs49014747
Full Text :
https://doi.org/10.1212/WNL.0000000000000305