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Mitochondrial dysfunction associated with a mutation in the Notch3gene in a CADASIL family
- Source :
- Neurology (Ovid); October 2001, Vol. 57 Issue: 7 p1235-1238, 4p
- Publication Year :
- 2001
-
Abstract
- Cerebral autosomal arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is characterized by recurrent subcortical ischemic strokes and dementia caused by mutations in the Notch3gene. In Drosophila melanogaster,Notch signaling has a pleiotropic effect, affecting most tissues of the organism during development.
Details
- Language :
- English
- ISSN :
- 00283878 and 1526632X
- Volume :
- 57
- Issue :
- 7
- Database :
- Supplemental Index
- Journal :
- Neurology (Ovid)
- Publication Type :
- Periodical
- Accession number :
- ejs49033073