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A magnetic resonance imaging study of the cervical cord of patients with CADASIL

Authors :
Rocca, M.A.
Filippi, M.
Herzog, J.
Sormani, M.P.
Dichgans, M.
Yousry, T.A.
Source :
Neurology (Ovid); May 2001, Vol. 56 Issue: 10 p1392-1394, 3p
Publication Year :
2001

Abstract

The authors obtained MR and magnetization transfer (MT) imaging of the cervical cord from 25 patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). They found no conventional MR abnormalities, but a reduced peak height of the MT ratio (MTR) histogram. This suggests a reduced amount of “truly” normal cord tissue in CADASIL. A significant correlation was found between the extent of brain lesions and cord MTR, suggesting wallerian degeneration as the substrate of the cord MTR changes.

Details

Language :
English
ISSN :
00283878 and 1526632X
Volume :
56
Issue :
10
Database :
Supplemental Index
Journal :
Neurology (Ovid)
Publication Type :
Periodical
Accession number :
ejs49033206