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Absence of genetic linkage of CharcotMarieTooth disease HMSN Ia with chromosome 1 gene markers
- Source :
- Neurology (Ovid); June 1989, Vol. 39 Issue: 6 p844-846, 3p
- Publication Year :
- 1989
-
Abstract
- We previously reported a large Charcot-Marie-Tooth family not linked to the Duffy blood group marker, supporting the existence of genetic heterogeneity in this neuropathy. In order to investigate the possibility of another disease locus on chromosome 1, we analyzed this family further, using DNA polymorphisms of 6 genes. Absence of linkage makes a second disease locus on chromosome 1 unlikely.
Details
- Language :
- English
- ISSN :
- 00283878 and 1526632X
- Volume :
- 39
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- Neurology (Ovid)
- Publication Type :
- Periodical
- Accession number :
- ejs49034974