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HHV8 and AIDSrelated CNS lymphoma

Authors :
Morgello, Susan
Tagliati, Michele
Ewart, Michelle R.
Source :
Neurology (Ovid); May 1997, Vol. 48 Issue: 5 p1333-1335, 3p
Publication Year :
1997

Abstract

Human herpesvirus 8 (HHV-81, the Kaposi's sarcoma (KS)-associated herpesvirus, is closely related to the transforming Epstein-Barr virus (EBV) and may be detected in AIDS-related, EBV-containing, body-cavity-based lymphomas. Accordingly, we analyzed 27 EBV-positive, AIDS-related CNS lymphomas for HHV-8 sequences. Only one tumor yielded HHV-8 sequences; this tumor arose in a patient with concomitant systemic lymphoma and a history of KS. We conclude that HHV-8 is unlikely to have a major role in the pathogenesis of AIDS-related, EBV-associated CNS lymphomas.

Details

Language :
English
ISSN :
00283878 and 1526632X
Volume :
48
Issue :
5
Database :
Supplemental Index
Journal :
Neurology (Ovid)
Publication Type :
Periodical
Accession number :
ejs49040607