Sequential Second Free Bone Flaps for Reconstruction of Metachronous Mandibular Defects

The purpose of this study was to identify patients who had previously undergone composite resection of a primary carcinoma of the oral cavity and immediate mandibular reconstruction with an osteocutaneous free flap and subsequently developed a local recurrence or a second metachronous tumor that required a second composite resection and immediate mandibular reconstruction with a second osteocutaneous free flap, in order to evaluate bone-to-bone healing of the two vascularized bone grafts and the long-term survival of these patients.