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Alleviation of Acute and Chronic Graft-Versus-Host Disease in a Murine Model Is Associated with Glucocerebroside-Enhanced Natural Killer T Lymphocyte Plasticity
- Source :
- Transplantation; February 2007, Vol. 83 Issue: 4 p458-467, 10p
- Publication Year :
- 2007
-
Abstract
- Natural killer T (NKT) lymphocytes play a role in graft-versus-host disease GVHD (GVHD). Glucocerebroside (GC) is a naturally occurring glycolipid that plays a role in the immune modulation of NKT lymphocytes. This study aims to determine the effect of GC in murine models of semiallogeneic/acute and chronic GVHD.
Details
- Language :
- English
- ISSN :
- 00411337 and 15346080
- Volume :
- 83
- Issue :
- 4
- Database :
- Supplemental Index
- Journal :
- Transplantation
- Publication Type :
- Periodical
- Accession number :
- ejs49263648
- Full Text :
- https://doi.org/10.1097/01.tp.0000252783.66886.f3