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Reduction of circulating redox-active iron by apotransferrin protects against renal ischemia-reperfusion injury1
- Source :
- Transplantation; March 2004, Vol. 77 Issue: 5 p669-675, 7p
- Publication Year :
- 2004
-
Abstract
- Warm ischemia-reperfusion (I/R) injury plays an important role in posttransplant organ failure. In particular, organs from marginal donors suffer I/R injury. Although iron has been implicated in the pathophysiology of renal I/R injury, the mechanism of iron-mediated injury remains to be established. The authors therefore investigated the role of circulating redox-active iron in an experimental model for renal I/R injury.
Details
- Language :
- English
- ISSN :
- 00411337 and 15346080
- Volume :
- 77
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Transplantation
- Publication Type :
- Periodical
- Accession number :
- ejs49275358
- Full Text :
- https://doi.org/10.1097/01.TP.0000115002.28575.E7