Monitoring the Efficacy of Chloroquine-Primaquine Therapy for Uncomplicated Plasmodium vivaxMalaria in the Main Transmission Hot Spot of Brazil

Authors :: Ladeia-Andrade, Simone
Menezes, Maria José
de Sousa, Taís Nóbrega
Silvino, Ana Carolina R.
de Carvalho, Jaques F.
Salla, Laís C.
Nery, Odaílton A.
de Melo, Gladson N. P.
Corder, Rodrigo M.
Rodrigues, Priscila T.
Ferreira, Marcelo U.
Source :: Antimicrobial Agents and Chemotherapy; March 2019, Vol. 63 Issue: 5
Publication Year :: 2019
Abstract: Emerging Plasmodium vivaxresistance to chloroquine (CQ) may undermine malaria elimination efforts in South America. CQ-resistant P. vivaxhas been found in the major port city of Manaus but not in the main malaria hot spots across the Amazon Basin of Brazil, where CQ is routinely coadministered with primaquine (PQ) for radical cure of vivax malaria.

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