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Heterogeneity of 68Ga-PSMA PET/CT Uptake in Fibrous Dysplasia

Authors :
Plouznikoff, Nicolas
Garcia, Camilo
Artigas, Carlos
Entezari, Kim
Flamen, Patrick
Source :
Clinical Nuclear Medicine; 20240101, Issue: Preprints
Publication Year :
2024

Abstract

Fibrous dysplasia is an uncommon benign bone pathology with only rare potential for malignant transformation. We describe the heterogeneous uptake of fibrous dysplasia of a whole rib on 68Ga-labeled prostate-specific membrane antigen (PSMA) PET/CT. 68Ga-PSMA binds to PSMA-expressing prostate cancer cells, but it can also bind to the neovasculature of various solid tumors, as well as to some benign lesions. 68Ga-PSMA expression in fibrous dysplasia should not automatically be equated with malignant transformation or confused with prostate cancer metastases.

Details

Language :
English
ISSN :
03639762 and 15360229
Issue :
Preprints
Database :
Supplemental Index
Journal :
Clinical Nuclear Medicine
Publication Type :
Periodical
Accession number :
ejs50593594
Full Text :
https://doi.org/10.1097/RLU.0000000000002609