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Gentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG): a randomised non-inferiority trial

Authors :
Ross, Jonathan D C
Brittain, Clare
Cole, Michelle
Dewsnap, Claire
Harding, Jan
Hepburn, Trish
Jackson, Louise
Keogh, Matthew
Lawrence, Tessa
Montgomery, Alan A
Roberts, Tracy E
Sprange, Kirsty
Tan, Wei
Thandi, Sukhwinder
White, John
Wilson, Janet
Duley, Lelia
Source :
The Lancet; June 2019, Vol. 393 Issue: 10190 p2511-2520, 10p
Publication Year :
2019

Abstract

Gonorrhoea is a common sexually transmitted infection for which ceftriaxone is the current first-line treatment, but antimicrobial resistance is emerging. The objective of this study was to assess the effectiveness of gentamicin as an alternative to ceftriaxone (both combined with azithromycin) for treatment of gonorrhoea.

Details

Language :
English
ISSN :
01406736 and 1474547X
Volume :
393
Issue :
10190
Database :
Supplemental Index
Journal :
The Lancet
Publication Type :
Periodical
Accession number :
ejs51011831
Full Text :
https://doi.org/10.1016/S0140-6736(18)32817-4