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Positive Impact of Genetic Test on the Management and Outcome of Patients With Paraganglioma and/or Pheochromocytoma.

Authors :
Buffet, Alexandre
Ben Aim, Laurène
Leboulleux, Sophie
Drui, Delphine
Vezzosi, Delphine
Libé, Rossella
Ajzenberg, Christiane
Bernardeschi, Daniele
Cariou, Bertrand
Chabolle, Frédéric
Chabre, Olivier
Darrouzet, Vincent
Delemer, Brigitte
Desailloud, Rachel
Goichot, Bernard
Esvant, Annabelle
Offredo, Lucile
Herman, Philippe
Laboureau, Sandrine
Lefebvre, Hervé
Pierre, Peggy
Raingeard, Isabelle
Reznik, Yves
Sadoul, Jean-Louis
Hadoux, Julien
Tabarin, Antoine
Tauveron, Igor
Zenaty, Delphine
Favier, Judith
Bertherat, Jérôme
Baudin, Eric
Amar, Laurence
Gimenez-Roqueplo, Anne-Paule
Source :
The Journal of Clinical Endocrinology & Metabolism; April 2019, Vol. 104 Issue: 4 p1109-1118, 10p
Publication Year :
2019

Abstract

Pheochromocytomas and paragangliomas (PPGLs) are characterized by a strong genetic component, with up to 40% of patients carrying a germline mutation in a PPGL susceptibility gene. International guidelines recommend that genetic screening be proposed to all patients with PPGL.

Details

Language :
English
ISSN :
0021972X and 19457197
Volume :
104
Issue :
4
Database :
Supplemental Index
Journal :
The Journal of Clinical Endocrinology & Metabolism
Publication Type :
Periodical
Accession number :
ejs51162415
Full Text :
https://doi.org/10.1210/jc.2018-02411