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Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition
- Source :
- Science Translational Medicine; December 2019, Vol. 11 Issue: 523
- Publication Year :
- 2019
-
Abstract
- Redox-sensitive mRNA nanoparticles help kill tumors by restoring p53 expression.
Details
- Language :
- English
- ISSN :
- 19466234 and 19466242
- Volume :
- 11
- Issue :
- 523
- Database :
- Supplemental Index
- Journal :
- Science Translational Medicine
- Publication Type :
- Periodical
- Accession number :
- ejs51822245
- Full Text :
- https://doi.org/10.1126/scitranslmed.aaw1565