Genomic information on Stenotrophomonas maltophiliaST264 isolated from a cystic fibrosis pediatric patient in Brazil

Stenotrophomonas maltophiliais one of the Gram-negative bacilli most frequently found in the airways of cystic fibrosis patients. This opportunistic pathogen is intrinsically multidrug-resistant, and therefore, its treatment presents a challenge. The genetic characterization of S. maltophiliais largely unknown, especially from those strains that colonize/infect the airways of cystic fibrosis patients. This work reports the draft genome sequences of three S. maltophiliaisolates recovered from the sputum of a cystic fibrosis pediatric patient in Southeast Brazil. Several resistance- and virulence-related genes were detected. Furthermore, one intact phage and one incomplete prophage region were also identified in all strains. Multilocus sequence typing showed that all strains belonged to a new sequence type (ST264). Interestingly, all S. maltophiliastrains were genetically identical, showing persistence for at least 16 months. To our knowledge, this is the first report of S. maltophiliadraft genome sequences obtained from a cystic fibrosis pediatric patient in Brazil.