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Potassium channels as potential drug targets for limb wound repair and regeneration.
- Source :
- Precision Clinical Medicine; March 2020, Vol. 3 Issue: 1 p22-33, 12p
- Publication Year :
- 2020
-
Abstract
- Ion channels are a large family of transmembrane proteins, accessible by soluble membrane-impermeable molecules, and thus are targets for development of therapeutic drugs. Ion channels are the second most common target for existing drugs, after G protein-coupled receptors, and are expected to make a big impact on precision medicine in many different diseases including wound repair and regeneration. Research has shown that endogenous bioelectric signaling mediated by ion channels is critical in non-mammalian limb regeneration. However, the role of ion channels in regeneration of limbs in mammalian systems is not yet defined.
Details
- Language :
- English
- ISSN :
- 20965303 and 25161571
- Volume :
- 3
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Precision Clinical Medicine
- Publication Type :
- Periodical
- Accession number :
- ejs52987257
- Full Text :
- https://doi.org/10.1093/pcmedi/pbz029