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Cancer-Associated Mutations in SF3B1 Exhibit Neomorphic Splicing Activity and Block Erythroid Differentiation

Authors :
Buonamici, Silvia
Perino, Samantha
Lim, Kian Huat
Feala, Jacob
Obeng, Esther A.
Aicher, Michelle
Aird, Daniel
Bailey, Suzanna
Berkenblit, Anna
Chan, Betty
Erik, Corcoran
Corson, Laura
Darman, Rachel
Fekkes, Peter
Furman, Richard R.
Keaney, Gregg F
Kumar, Pavan
Kunii, Kaiko
Lee, Linda
Mackenzie, Crystal
Park, Eunice
Puyang, Xiaoling
Selvaraj, Anand
Thomas, Michael
Wang, John
Warmuth, Markus
Yu, Lihua
Zhu, Ping
Mizui, Yoshiharu
Ebert, Benjamin L.
Smith, Peter G
Source :
Blood; December 2014, Vol. 124 Issue: 21 p4615-4615, 1p
Publication Year :
2014

Abstract

Buonamici: H3 Biomedicine: Employment. Perino:H3 Biomedicine: Employment. Lim:H3 Biomedicine: Employment. Feala:H3 Biomedicine: Employment. Aicher:H3 Biomedicine: Employment. Aird:H3 Biomedicine: Employment. Bailey:H3 Biomedicine: Employment. Berkenblit:H3 Biomedicine: Employment. Chan:H3 Biomedicine: Employment. Erik:H3 Biomedicine: Employment. Corson:H3 Biomedicine: Employment. Darman:H3 Biomedicine: Employment. Fekkes:H3 Biomedicine: Employment. Furman:Pharmacyclics: Consultancy, Speakers Bureau. Keaney:H3 Biomedicine: Employment. Kumar:Eisai: Employment. Kunii:H3 Biomedicine: Employment. Lee:H3 Biomedicine: Employment. Mackenzie:Eisai: Employment. Park:H3 Biomedicine: Employment. Puyang:H3 Biomedicine: Employment. Selvaraj:H3 Biomedicine: Employment. Thomas:H3 Biomedicine: Employment. Wang:H3 Biomedicine: Employment. Warmuth:H3 Biomedicine: Employment. Yu:H3 Biomedicine: Employment. Zhu:H3 Biomedicine: Employment. Mizui:H3 Biomedicine: Employment. Smith:H3 Biomedicine: Employment.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
124
Issue :
21
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs53021969
Full Text :
https://doi.org/10.1182/blood.V124.21.4615.4615
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