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Rigosertib Blocks RAS Signaling By Acting As a Small Molecule RAS Mimetic That Binds to the RAS-Binding Domains of RAS Effector Proteins

Authors :
Reddy, E. Premkumar
Divakar, Sai Krishna
Vasquez-Del Carpio, Rodrigo
Dutta, Kaushik
Baker, Stacey J
Reddy, Ramana
Aggarwal, Aneel K
Source :
Blood; December 2014, Vol. 124 Issue: 21 p5616-5616, 1p
Publication Year :
2014

Abstract

Reddy: Onconova Therapeutics Inc: Research Funding. Divakar:Onconova Therapeutics Inc: Research Funding. Vasquez-Del Carpio:Onconova Therapeutics Inc: Research Funding. Dutta:Onconova Therapeutics Inc: Research Funding. Baker:Onconova Therapeautics Inc: Consultancy. Reddy:Onconova Therapeutics Inc: Consultancy. Aggarwal:Onconova Therapeutics Inc: Research Funding.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
124
Issue :
21
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs53033898
Full Text :
https://doi.org/10.1182/blood.V124.21.5616.5616