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In vivoformation of Cu(DDC)2complex induced by nanomedicine for mesothelioma chemotherapy

Authors :
Zhang, Yixin
Ding, Shunjie
Li, Junhua
Peng, Xinyu
Li, Jing
Chang, Jing
Gao, Wenxia
He, Bin
Source :
Chinese Chemical Letters; December 2020, Vol. 31 Issue: 12 p3168-3172, 5p
Publication Year :
2020

Abstract

The in vivoformation of Cu(DDC)2complex was induced by disulfiram and Cu2+released from PLGA nanoparticles. This strategy avoids many obstacles in the use of Cu(DDC)2complex as a chemotherapeutic and exhibits excellent inhibition to mesothelioma.

Details

Language :
English
ISSN :
10018417
Volume :
31
Issue :
12
Database :
Supplemental Index
Journal :
Chinese Chemical Letters
Publication Type :
Periodical
Accession number :
ejs53264180
Full Text :
https://doi.org/10.1016/j.cclet.2020.04.051