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First Clinical Case of In VivoAcquisition of DHA-1 Plasmid-Mediated AmpC in a Salmonella entericasubsp. entericaIsolate

Authors :
Clément, Mathieu
Keller, Peter M.
Bernasconi, Odette J.
Stirnimann, Guido
Frey, Pascal M.
Bloemberg, Guido V.
Sendi, Parham
Endimiani, Andrea
Source :
Antimicrobial Agents and Chemotherapy; July 2019, Vol. 63 Issue: 10
Publication Year :
2019

Abstract

A pan-susceptible Salmonella entericaserovar Worthington isolate was detected in the stool of a man returning from Sri Lanka. Under ceftriaxone treatment, a third-generation cephalosporin (3GC)-resistant SalmonellaWorthington was isolated after 8 days. Molecular analyses indicated that the two isolates were identical. However, the latter strain acquired a blaDHA-1-carrying IncFII plasmid probably from a Citrobacter amalonaticusisolate colonizing the gut.

Details

Language :
English
ISSN :
00664804 and 10986596
Volume :
63
Issue :
10
Database :
Supplemental Index
Journal :
Antimicrobial Agents and Chemotherapy
Publication Type :
Periodical
Accession number :
ejs53327800
Full Text :
https://doi.org/10.1128/AAC.00992-19