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Editing a ?-Globin Repressor Binding Site Restores Fetal Hemoglobin Synthesis and Corrects the Phenotype of Sickle Cell Disease Erythrocytes

Authors :
Weber, Leslie
Frati, Giacomo
Felix, Tristan
Wollenschlaeger, Clara
Casini, Antonio
Meneghini, Vasco
Masson, Cecile
De Cian, Anne
Chalumeau, Anne
Mavilio, Fulvio
Amendola, Mario
André, Isabelle
Cereseto, Anna
El Nemer, Wassim
Concordet, Jean-Paul
Giovannangeli, Carine
Cavazzana, Marina
Miccio, Annarita
Source :
Blood; November 2019, Vol. 134 Issue: Supplement 1 p4635-4635, 1p
Publication Year :
2019

Abstract

El Nemer: Hemanext: Other: Other. Cavazzana:SmartImmune: Other: Founder.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
134
Issue :
Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs53604384
Full Text :
https://doi.org/10.1182/blood-2019-123192