Number, type and cost of microbiological tests during HIV Pre-Exposure Prophylaxis: The experience of a French hospital

•Numerous microbiological tests are required for patients on PrEP.•Serology accounts for 98% of virological tests.•Molecular biology accounts for 63% of bacteriological tests.•Virological assays account for 37.7% of global test costs.•Bacteriological assays account for 62.3% of global test costs.•STDs are highly prevalent during the time course of PreEP.