Specific Class I HLA Supertypes but Not HLA Zygosity or Expression Are Associated with Outcomes following HLA-Matched Allogeneic Hematopoietic Cell Transplant: HLA Supertypes Impact Allogeneic HCT Outcomes

•HLA zygosity, supertypes, and expression are evaluated in post-transplant outcomes.•HLA-B62 supertype is associated with reduced transplant-related mortality.•HLA-B27 supertype is correlated with worse disease free-survival in acute myeloid leukemia.•No association exists between HLA zygosity or expression and transplant outcomes.