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Immune Escape in Prostate Cancer

Authors :
Reva, Boris A.
Omelchenko, Tatiana
Nair, Sujit S.
Tewari, Ashutosh K.
Source :
Urologic Clinics of North America; November 2020, Vol. 47 Issue: 4, Number 4 Supplement 1 pe9-e16, 8p
Publication Year :
2020

Abstract

Complex immune evasion mechanisms and lack of biomarkers predicting responsiveness to immune checkpoint blockade therapies compromise immunotherapy’s therapeutic efficacy for patients with prostate cancer. The authors review established and nominated immune evasion mechanisms in prostate cancer and discuss how the precise treatment strategies can be developed to improve efficacy of immunotherapy.

Details

Language :
English
ISSN :
00940143
Volume :
47
Issue :
4, Number 4 Supplement 1
Database :
Supplemental Index
Journal :
Urologic Clinics of North America
Publication Type :
Periodical
Accession number :
ejs54518788
Full Text :
https://doi.org/10.1016/j.ucl.2020.10.004