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Efficient Route to 1,3-Di-N-imidazolylbenzene. A Comparison of Monodentate vs Bidentate Carbenes in Pd-Catalyzed Cross Coupling

Authors :
Vargas, V. C.
Rubio, R. J.
Hollis, T. K.
Salcido, M. E.
Source :
Organic Letters; December 2003, Vol. 5 Issue: 25 p4847-4849, 3p
Publication Year :
2003

Abstract

<UFIGR ID="ol035906zn00001">A new bis(carbene) ligand architecture has been developed and was evaluated in the Suzuki−Miyaura cross-coupling reaction of various aryl halides with phenylboronic acid. Several new bis(carbene) ligands were tested in different carbene:Pd ratios. Pd(OAc)<INF>2</INF> and Pd<INF>2</INF>(dba)<INF>3</INF> were compared for efficiency as a Pd source. It was found that the Pd(OAc)<INF>2</INF>/bis(carbene) system formed a catalyst for the activation of chlorobenzene.

Details

Language :
English
ISSN :
15237060 and 15237052
Volume :
5
Issue :
25
Database :
Supplemental Index
Journal :
Organic Letters
Publication Type :
Periodical
Accession number :
ejs5477590