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MicroRNA-506-3p increases the response to PARP inhibitors and cisplatin by targeting EZH2/β-catenin in serous ovarian cancers
- Source :
- Translational Oncology; February 2021, Vol. 14 Issue: 2
- Publication Year :
- 2021
-
Abstract
- •EZH2 is considered as a direct target of miR-506-3p.•MiR-506-3p overexpression decreased the level of β-catenin.•MiR-506-3p increases response to PARP inhibitors and cisplatin in serous ovarian cancer by targeting EZH2/β-catenin pathway.
Details
- Language :
- English
- ISSN :
- 19447124 and 19365233
- Volume :
- 14
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Translational Oncology
- Publication Type :
- Periodical
- Accession number :
- ejs54840468
- Full Text :
- https://doi.org/10.1016/j.tranon.2020.100987