Event-related potentials and deep grey matter atrophy in multiple sclerosis: exploring the possible associations with cognition

•We explored the relationship between event-related potentials, deep gray matter atrophy and cognition in MS•Cortex volume emerged as the most significant predictor of the P300 amplitude.•The amygdala and hippocampal volumes were found to influence P300 latency•The combination of structural MRI and neurophysiological techniques could improve the understanding of CI in MS