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Risk factors of de novomalignancies after liver transplantation: a French national study on 11004 adult patients

Authors :
Altieri, Mario
Sérée, Olivier
Lobbedez, Thierry
Segol, Philippe
Abergel, Armand
Blaizot, Xavier
Boillot, Olivier
Boudjema, Karim
Coilly, Audrey
Conti, Filomena
Chazouillères, Olivier
Debette-Gratien, Maryline
Dharancy, Sébastien
Durand, François
Duvoux, Christophe
Francoz, Claire
Gugenheim, Jean
Hardwigsen, Jean
Houssel-Debry, Pauline
Kamar, Nassim
Latournerie, Marianne
Lebray, Pascal
Leroy, Vincent
Neau-Cransac, Martine
Pageaux, Georges-Philippe
Radenne, Sylvie
Salamé, Ephrem
Saliba, Faouzi
Samuel, Didier
Vanlemmens, Claire
Besch, Camille
Launoy, Guy
Dumortier, Jérôme
Source :
Clinics and Research in Hepatology and Gastroenterology; July 2021, Vol. 45 Issue: 4
Publication Year :
2021

Abstract

•After liver transplantation (LT), de novomalignancies are one of the leading causes of late mortality.•Risk factors of de novomalignancies in a large cohort of LT recipients (n=11004) are described using Fine and Gray competing risks regression analysis.•The overall incidence of de novo malignancies was 13.45%.•Were significant risk factors for de novomalignancy: recipient age, male gender, non-living donor, a first LT and the type of initial liver disease.•Initial immunosuppressive regimen had no significant impact.

Details

Language :
English
ISSN :
22107401
Volume :
45
Issue :
4
Database :
Supplemental Index
Journal :
Clinics and Research in Hepatology and Gastroenterology
Publication Type :
Periodical
Accession number :
ejs55534145
Full Text :
https://doi.org/10.1016/j.clinre.2020.07.019