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A New Panel-Estimated GFR, Including β2-Microglobulin and β-Trace Protein and Not Including Race, Developed in a Diverse Population

Authors :
Inker, Lesley A.
Couture, Sara J.
Tighiouart, Hocine
Abraham, Alison G.
Beck, Gerald J.
Feldman, Harold I.
Greene, Tom
Gudnason, Vilmundur
Karger, Amy B.
Eckfeldt, John H.
Kasiske, Bertram L.
Mauer, Michael
Navis, Gerjan
Poggio, Emilio D.
Rossing, Peter
Shlipak, Michael G.
Levey, Andrew S.
Andresdottir, Margret B.
Gudmundsdottir, Hrefna
Indridason, Olafur S.
Palsson, Runolfur
Kimmel, Paul
Weir, Matt
Kalil, Roberto
Pesavento, Todd
Porter, Anna
Taliercio, Jonathan
Hsu, Chi-yuan
Chen, Jing
Sinkeler, Steef
Wyatt, Christina
Krishnasami, Zipporah
Hellinger, James
Margolick, Joseph
Kingsley, Lawrence
Witt, Mallory
Wolinsky, Steven
Shafi, Tariq
Post, Wendy
Doria, Alessandro
Parving, Hans-Henrik
Source :
American Journal of Kidney Diseases; May 2021, Vol. 77 Issue: 5 p673-683.e1
Publication Year :
2021

Abstract

Glomerular filtration rate (GFR) estimation based on creatinine and cystatin C (eGFRcr-cys) is more accurate than estimated GFR (eGFR) based on creatinine or cystatin C alone (eGFRcror eGFRcys, respectively), but the inclusion of creatinine in eGFRcr-cysrequires specification of a person’s race. β2-Microglobulin (B2M) and β-trace protein (BTP) are alternative filtration markers that appear to be less influenced by race than creatinine is.

Details

Language :
English
ISSN :
02726386 and 15236838
Volume :
77
Issue :
5
Database :
Supplemental Index
Journal :
American Journal of Kidney Diseases
Publication Type :
Periodical
Accession number :
ejs55534971
Full Text :
https://doi.org/10.1053/j.ajkd.2020.11.005