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Soluble Interleukin-6 Receptor in the COVID-19 Cytokine Storm Syndrome
- Source :
- Cell Reports Medicine; 20210101, Issue: Preprints
- Publication Year :
- 2021
-
Abstract
- Data suggest that interleukin (IL)-6 blockade could reduce mortality in severe COVID-19, yet IL-6 is only modestly elevated in most patients. Chen et al. describe the role of soluble interleukin-6 receptor (sIL-6R) in IL-6 trans-signaling, and how understanding the IL-6:sIL-6R axis might help define and treat COVID-19 cytokine storm syndrome.
Details
- Language :
- English
- ISSN :
- 26663791
- Issue :
- Preprints
- Database :
- Supplemental Index
- Journal :
- Cell Reports Medicine
- Publication Type :
- Periodical
- Accession number :
- ejs55873559
- Full Text :
- https://doi.org/10.1016/j.xcrm.2021.100269