Back to Search
Start Over
Prevotelladiversity, niches and interactions with the human host
- Source :
- Nature Reviews Microbiology; September 2021, Vol. 19 Issue: 9 p585-599, 15p
- Publication Year :
- 2021
-
Abstract
- The genus Prevotellaincludes more than 50 characterized species that occur in varied natural habitats, although most Prevotellaspp. are associated with humans. In the human microbiome, Prevotellaspp. are highly abundant in various body sites, where they are key players in the balance between health and disease. Host factors related to diet, lifestyle and geography are fundamental in affecting the diversity and prevalence of Prevotellaspecies and strains in the human microbiome. These factors, along with the ecological relationship of Prevotellawith other members of the microbiome, likely determine the extent of the contribution of Prevotellato human metabolism and health. Here we review the diversity, prevalence and potential connection of Prevotellaspp. in the human host, highlighting how genomic methods and analysis have improved and should further help in framing their ecological role. We also provide suggestions for future research to improve understanding of the possible functions of Prevotellaspp. and the effects of the Western lifestyle and diet on the host–Prevotellasymbiotic relationship in the context of maintaining human health.
Details
- Language :
- English
- ISSN :
- 17401526 and 17401534
- Volume :
- 19
- Issue :
- 9
- Database :
- Supplemental Index
- Journal :
- Nature Reviews Microbiology
- Publication Type :
- Periodical
- Accession number :
- ejs56493202
- Full Text :
- https://doi.org/10.1038/s41579-021-00559-y