Impact of Comorbidities and Concomitant Medications on Survival of Patients with Chronic Lymphocytic Leukemia: Analysis of an Unselected Patient Population from East Bohemia

Introduction: Chronic lymphocytic leukemia (CLL) is a disease with an extremely variable clinical course. Biological features of CLL with impact on prognosis have been well defined over the last decades, but there is little data on how comorbidities of CLL patients (pts) may influence overall survival. Importantly, most of the studies on this topic included selected patient populations from secondary or tertiary centers with significant bias caused by high proportion of referred patients with unfavourable disease course.