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Venetoclax Is Safe and Efficacious in Relapsed/ Refractory AML

Authors :
Ganzel, Chezi
Ram, Ron
Gural, Alexander
Wolach, Ofir
Gino-Moor, Sharon
Vainstein, Vladimir
Nachmias, Boaz
Apel, Arie
Koren-Michowitz, Maya
Pasvolsky, Oren
Yerushalmi, Ronit
Danylesko, Ivetta
Cohen, Yoseph
Perets, Galit
Moshe, Yakir
Zektzer, Miri
Yeganeh, Shay
Rowe, Jacob M.
Ofran, Yishai
Source :
Blood; November 2019, Vol. 134 Issue: 1, Number 1 Supplement 1 p5091-5091, 1p
Publication Year :
2019

Abstract

Introduction:On November 2018 the FDA approved the treatment of venetoclax together with hypomethylating agent (HMA) or low dose cytarabine (LDAC) for newly diagnosed AML patients who cannot tolerate intensive chemotherapy. There is limited data regarding the efficacy and safety of venetoclax in the setting of relapsed/refractory patients who received intensive chemotherapy for their disease.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
134
Issue :
1, Number 1 Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs56878548
Full Text :
https://doi.org/10.1182/blood-2019-125662