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Aztreonam-Avibactam Susceptibility Testing Program for Metallo-Beta-Lactamase-Producing Enterobacteralesin the Antibiotic Resistance Laboratory Network, March 2019 to December 2020

Authors :
Bhatnagar, Amelia
Boyd, Sandra
Sabour, Sarah
Bodnar, Janine
Nazarian, Elizabeth
Peinovich, Nadine
Wagner, Christine
Craft, Bradley
Snippes Vagnone, Paula
Simpson, Justin
Stone, Victoria N.
Therrien, Michelle
Bateman, Allen
Lower, Danielle
Huang, Jennifer Y.
Gumbis, Stephanie
Lonsway, David
Lutgring, Joseph D.
Karlsson, Maria
Brown, Allison C.
Source :
Antimicrobial Agents and Chemotherapy; July 2021, Vol. 65 Issue: 8
Publication Year :
2021

Abstract

Aztreonam-avibactam is a drug combination pending phase 3 clinical trials and is suggested for treatment of severe infections caused by metallo-beta-lactamase (MBL)-producing Enterobacteralesby combining ceftazidime-avibactam and aztreonam. Beginning in 2019, four Antibiotic Resistance Laboratory Network regional laboratories offered aztreonam-avibactam susceptibility testing by broth microdilution.

Details

Language :
English
ISSN :
00664804 and 10986596
Volume :
65
Issue :
8
Database :
Supplemental Index
Journal :
Antimicrobial Agents and Chemotherapy
Publication Type :
Periodical
Accession number :
ejs57064053
Full Text :
https://doi.org/10.1128/AAC.00486-21