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High Seroprevalence of Neutralizing Capacity against Human Metapneumovirus in All Age Groups Studied in Bonn, Germany
- Source :
- Clinical and Vaccine Immunology (formerly CDLI); March 2010, Vol. 17 Issue: 3 p481-484, 4p
- Publication Year :
- 2010
-
Abstract
- ABSTRACTHuman metapneumovirus (hMPV) infections occur frequently despite high rates of perpetual seroprevalence for all age groups. Analyses of ~2,000 archived, randomly selected serum samples demonstrated that neutralizing capacities remain high, with a minor decrease for individuals over 69 years of age, leading to the hypothesis that reinfections occur because humoral immune responses play minor roles in the clearance of hMPV infections.
Details
- Language :
- English
- ISSN :
- 15566811 and 1556679X
- Volume :
- 17
- Issue :
- 3
- Database :
- Supplemental Index
- Journal :
- Clinical and Vaccine Immunology (formerly CDLI)
- Publication Type :
- Periodical
- Accession number :
- ejs57510590
- Full Text :
- https://doi.org/10.1128/CVI.00398-09